Purification methods for neuronal K+ channels
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولKetamine and propofol differentially inhibit human neuronal K(+) channels.
BACKGROUND AND OBJECTIVE Interaction of intravenous anaesthetic agents with voltage-dependent potassium channels significantly correlates with clinical concentrations. If potassium channels were to play an important part in anaesthesia, one might expect different effects at the molecular level of those anaesthetics that show different clinical effects. Our aim was to analyse the interaction of ...
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ATP-sensitive K+ (KATP) channels are expressed in many different tissues including the brain,where they couple energy metabolism to cellular excitability.Although their classical role in insulin secretion in pancreatic β-cells is well understood, their neuronal function remains unclear.Now,an important study using knockout mice provides clear evidence that neuronal KATP channels are crucial pla...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1989
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj2640622